This article updates the 1999 British Andrology Society (BAS) guidelines for the screening of sperm donors and the 2000 British Fertility Society (BFS) guidelines for the screening of egg and embryo donors and combines the new recommendations into a single document. This was achieved by a multidisciplinary working group composed of representatives from the Association of Biomedical Andrologists, the Association of Clinical Embryologists, the BAS, the BFS and the Royal College of Obstetricians and Gynecologists. The major changes to the guidelines include a requirement to consider a donor's risk of transmissible spongiform encephalopathies and the recommendation to screen for human T cell lymphotropic viruses 1 and 2. The role of nucleic amplification tests for the detection of blood borne viruses such as HIV is discussed, but it remains the recommendation that this be achieved by serological testing to detect antibody or antigen as appropriate with a quarantine period of 180 days.
Introduces the basic concepts of transfusion science, including the application of genetics and immunology to transfusion practice. Utilizes terminology needed to understand and communicate about transfusion practice. Presents an understanding of major blood group systems, and component therapy and explains the significance these have in transfusion science. Illustrates and provides opportunity to practice the basic techniques used in transfusion service. Provides practice in pretransfusion testing, including ABO typing, Rh typing and antibody screening. Describes blood products (components and fractions) and considers donor issues and special treatment of blood products. Prerequisites: All of MLSC Level 1 courses.