Nonsteroidal enteropathy

The diagnosis of IBD is usually supported by colonoscopy. Laboratory testing should include a complete blood count, fecal leukocyte level, erythrocyte sedimentation rate, and fecal calprotectin level. 17 An elevated fecal calprotectin level is emerging as a reliable way to establish the diagnosis of IBD as distinguished from IBS, and to monitor its activity once diagnosed. 17 Fecal calprotectin level is a newer stool screen that reflects fecal leukocyte activity; the stool sample can be collected by the patient at home because calprotectin is stable in stool samples for up to seven days at room temperature. In adults, fecal calprotectin level is 93 percent sensitive and 96 percent specific for IBD, although specificity is less (76 percent) in children and teenagers. 18 Routine screening with fecal calprotectin level could result in a 67 percent reduction in the use of colonoscopies for IBD diagnosis in adults, because only those with a positive result would need them ( Figure 2 ) . 18

Nonsteroidal enteropathy

nonsteroidal enteropathy

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