Some side effects of prohormone supplementation can include acne breakouts, temporary hair loss, and increased sensitivity of the breast tissue. To help minimize these undesirable side effects, many users add a process known as post cycle therapy. Completing post cycle therapy entails taking an additional supplement that will offset spikes in testosterone levels and clear any toxins that have accumulated in the liver. Since prohormones are processed and broken down in the liver, it can add more stress on this organ than normal. These supplements can also lead to increases in blood pressure, which is another reason why post cycle therapy is a good idea.
Steroids can worsen existing skin pathologies. Athletes being treated for acne often stop responding to normal treatment regimens if they also continue to use the drugs. Some cases of comparatively benign acne can progress to the disfiguring inflammatory types. Psoriasis is an autoimmune disease in which, for unknown reasons, immune cells attack skin cells, resulting in red, scaly patches. One bodybuilder had controlled his psoriasis condition through the use of a topical cream, but when he began using steroids, his condition considerably deteriorated. Eventually his psoriasis became resistant to treatment. But when he stopped using steroids, the psoriasis stabilized and again responded to simple skin-cream treatment. 6