It is necessary to control blood pressure and pulse rate every 2 weeks during the first 2 months of treatment and then 1 time per month. The emergence during therapy of chest pain, progressive dyspnoea (breathing problems) and edema of the lower extremities may indicate the development of pulmonary hypertension (in this case, be sure to consult a doctor).
It should be borne in mind that sibutramine can reduce saliva and contribute to the development of caries, periodontal diseases, candidiasis and discomfort in the mouth. During treatment it is recommended to limit the consumption of alcohol. It should not be used during the drivers of vehicles and people skills relate to the high concentration of attention.